This study aimed to analyse, for the first time, five MHC class II polymorphic Alu insertions in a population with a strong Sub‐Saharan African genetic background: the Ngazidja islanders and… Click to show full abstract
This study aimed to analyse, for the first time, five MHC class II polymorphic Alu insertions in a population with a strong Sub‐Saharan African genetic background: the Ngazidja islanders and compare its allelic and haplotypic data with Worldwide populations. The genotyping was performed in 80 individuals, using simple PCR and agarose gel electrophoresis methods. Allele and haplotype frequencies, genetic diversity, Hardy–Weinberg equilibrium deviations, normalized deviate of homozygotes and pairwise linkage disequilibrium were estimated. The phylogenetic analyses included the available population data.
               
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