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Multiple sclerosis (MS) is a chronic neurological disease believed to be caused by autoimmune pathogenesis. The aetiology is likely explained by a complex interplay between inherited and environmental factors. Genetic… Click to show full abstract
Multiple sclerosis (MS) is a chronic neurological disease believed to be caused by autoimmune pathogenesis. The aetiology is likely explained by a complex interplay between inherited and environmental factors. Genetic investigations into MS have been conducted for over 50 years, yielding >100 associations to date. Globally, the strongest linkage is with the human leukocyte antigen (HLA) HLA‐DRB5*01:01:01‐DRB1*15:01:01‐DQA1*01:02:01‐DQB1*06:02:01 haplotype.
Keywords:
hla class;
hla;
high resolution;
resolution hla;
multiple sclerosis
Journal Title: International Journal of Immunogenetics
Year Published: 2022
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Journal Title: International Journal of Immunogenetics
Year Published: 2022
Link to full text (if available)
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recommendations!