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Low expression of miR‐204 is associated with expression of CD34 and poor performance status in denovo AML

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Acute myeloid leukemia (AML) is the most common acute leukemia in adults. There is growing evidence that microRNAs (miRNAs) provide prognostic information in AML. MiR‐204 has a tumor suppressor function,… Click to show full abstract

Acute myeloid leukemia (AML) is the most common acute leukemia in adults. There is growing evidence that microRNAs (miRNAs) provide prognostic information in AML. MiR‐204 has a tumor suppressor function, and several studies have proven its role in solid cancers. The aim of this work is to evaluate the level of expression of miR‐204 in adults newly diagnosed with AML with normal karyotype and to correlate its level of expression with disease outcome and different prognostic factors.

Keywords: expression; mir 204; aml; low expression; expression mir

Journal Title: International Journal of Laboratory Hematology
Year Published: 2020

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