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Application of clot‐fibrinolysis waveform analysis to assessment of in vitro effects of direct oral anticoagulants on fibrinolysis

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Acceleration of fibrinolysis by direct oral anticoagulants (DOACs) has been reported by several groups, suggesting contribution of not only anticoagulant but also fibrinolytic effects to the therapeutic efficacy. The present… Click to show full abstract

Acceleration of fibrinolysis by direct oral anticoagulants (DOACs) has been reported by several groups, suggesting contribution of not only anticoagulant but also fibrinolytic effects to the therapeutic efficacy. The present study aims to evaluate the usability of clot‐fibrinolysis waveform analysis (CFWA) for assessment of in vitro effects of DOACs on fibrinolysis.

Keywords: oral anticoagulants; direct oral; clot fibrinolysis; fibrinolysis waveform; waveform analysis; fibrinolysis

Journal Title: International Journal of Laboratory Hematology
Year Published: 2020

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