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Changes in peripheral blood cellular morphology as diagnostic markers for COVID‐19 infection

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Real‐time reverse‐transcriptase polymerase chain reaction (RT‐PCR) assays were established to detect severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2). However, due to the high rate of false negative results, additional tests as… Click to show full abstract

Real‐time reverse‐transcriptase polymerase chain reaction (RT‐PCR) assays were established to detect severe acute respiratory syndrome‐coronavirus 2 (SARS‐CoV‐2). However, due to the high rate of false negative results, additional tests as computed tomography (CT) scans of the chest and blood chemistry are required to properly diagnose COVID‐19 infection. Abnormal morphological changes of peripheral blood cells as granulocytic dysmorphism and abnormal reactive lymphocytes have been described in some cases. The aim of the present study was to investigate the morphological changes affecting all peripheral blood cells of COVID‐19 patients, in order to find any specific abnormalities that could help in the early diagnosis and/or prognosis.

Keywords: covid infection; changes peripheral; blood cellular; peripheral blood; blood

Journal Title: International Journal of Laboratory Hematology
Year Published: 2022

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