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PCR‐Fluo‐ASXL1‐FA: A fast, sensitive and inexpensive complementary method to detect ASXL1 mutations in haematological malignancies

The additional sex combs like 1 (ASXL1) gene is frequently mutated in a number of haematological neoplasms. The c.1934dupG, known to be the most common alteration in ASXL1, is associated… Click to show full abstract

The additional sex combs like 1 (ASXL1) gene is frequently mutated in a number of haematological neoplasms. The c.1934dupG, known to be the most common alteration in ASXL1, is associated with poor clinical outcome. A systematic determination of ASXL1 mutational status in myeloid malignancies is therefore necessary for prognostic stratification.

Keywords: asxl1 fast; fluo asxl1; fast sensitive; pcr fluo; inexpensive complementary; sensitive inexpensive

Journal Title: International Journal of Laboratory Hematology
Year Published: 2022

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