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Acute myeloid leukemia fusion genes can be found in CD33‐negative cells

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Targeted therapies and immunotherapies are emerging strategies for the treatment of leukemia. CD33 is a common and important therapeutic target for cellular immunotherapy or antibody immunotherapy. Drugs on targeting CD33… Click to show full abstract

Targeted therapies and immunotherapies are emerging strategies for the treatment of leukemia. CD33 is a common and important therapeutic target for cellular immunotherapy or antibody immunotherapy. Drugs on targeting CD33 are also emerging. However, acute myeloid leukemia (AML) relapse still occurs after treatment with targeted CD33, for which the mechanism is unknown.

Keywords: myeloid leukemia; genes found; leukemia fusion; leukemia; acute myeloid; fusion genes

Journal Title: International Journal of Laboratory Hematology
Year Published: 2022

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