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Adult mixed phenotype acute leukemia (MPAL): B/myeloid MPALisoMPO is distinct from other MPAL subtypes

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Myeloperoxidase (MPO) is considered a specific marker of myeloid/non‐monocytic lineage in the diagnosis of mixed phenotype acute leukemia (MPAL). However, the clinical significance of isolated dim MPO expression in otherwise… Click to show full abstract

Myeloperoxidase (MPO) is considered a specific marker of myeloid/non‐monocytic lineage in the diagnosis of mixed phenotype acute leukemia (MPAL). However, the clinical significance of isolated dim MPO expression in otherwise typical B lymphoblastic leukemia (B‐ALL; referred to as B/myeloid MPALisoMPO) in adult patients is unknown.

Keywords: mixed phenotype; phenotype acute; leukemia; acute leukemia; leukemia mpal; myeloid mpalisompo

Journal Title: International Journal of Laboratory Hematology
Year Published: 2022

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