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BACKGROUND The Patient Health Engagement Scale was designed to assess the emotional and psychological attitudes of patients' engagement along their healthcare management journey. AIM This study aimed to conduct psychometric testing of the Turkish version of the Patient Health Engagement Scale among patients with chronic diseases. DESIGN A cross-sectional validation study was conducted and reported according to the STROBE checklist. METHODS There were 520 patients who completed the scale between March 2017 and February 2018. The content, construct and concurrent validity were evaluated. The reliability of the scale was measured using internal consistency and construct reliability. Construct validity was examined using exploratory factor analysis and confirmatory factor analysis. RESULTS The scale's validity was enabled by the translation and back translation method. The content validity index of the scale was 0.88. Construct validity determined one factor. The total variance was calculated at 85.29%. The factor loads ranged between 0.86 and 0.95. The results of the confirmatory factor analysis showed goodness-of-fit indices in the excellent range according to the literature. The reliability of the scale was calculated at 0.95. CONCLUSION The scale was found to be a valid and reliable measurement tool to be used in identifying the engagement with health levels of patients with chronic diseases.