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Mastering an exhausting marathon: how CD8+ T cells fine‐tune metabolic fitness

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A recent study by Gabriel et al. provides novel insight into the metabolic pathways that contribute to T cell differentiation in chronic infection. The researchers discovered that metabolic plasticity and the… Click to show full abstract

A recent study by Gabriel et al. provides novel insight into the metabolic pathways that contribute to T cell differentiation in chronic infection. The researchers discovered that metabolic plasticity and the function of exhausted T cells is regulated via the TGF-β-mTOR signaling axis.

Keywords: mastering exhausting; fine tune; cells fine; exhausting marathon; cd8 cells; marathon cd8

Journal Title: Immunology and Cell Biology
Year Published: 2022

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