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Haemophagocytic lymphohistiocytosis (HLH) is a rare disorder with a poor prognosis characterised by substantial immune activation leading to end‐organ failure. In childhood, genetic defects that impair cytotoxic function of natural… Click to show full abstract
Haemophagocytic lymphohistiocytosis (HLH) is a rare disorder with a poor prognosis characterised by substantial immune activation leading to end‐organ failure. In childhood, genetic defects that impair cytotoxic function of natural killer cells and T cells. (HLH) are often identified. In adults, clinical manifestations are similar to those observed in children but the aetiology is often unclear.
Keywords:
analysis diagnostic;
lymphohistiocytosis;
centre analysis;
retrospective single;
single centre;
haemophagocytic lymphohistiocytosis
Journal Title: Internal Medicine Journal
Year Published: 2020
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Journal Title: Internal Medicine Journal
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!