LAUSR

Case report: We report a 17-year-old boy who presented at 6 months of age with persistence stridor and cough and a diagnosis of RRP – HPV-11 was made. Symptoms progressed and by 10 months laser microlaryngoscopy was required. In total he has had over 130 admissions to our hospital with over 80 surgical procedures. By 12 years the disease was affecting the trachea (70% obstruction), larynx and right main bronchus. By 13 years the disease was involving lung parenchyma with multiple cystic lesions seen on CT. He was requiring surgical intervention every 4–6 weeks. All adjuvant treatment modalities had failed to control the disease progression, some with an unacceptable side effect profile, including increased risk of malignancy and renal toxicity. Having exhausted standard treatments palliation was considered.