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Pathological profiles of systemic infections by Panton‐Valentine leukocidin‐positive, methicillin‐resistant Staphylococcus aureus strains in a murine model

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Staphylococcus aureus is one of the most common pathogens in hospital environment and community. Panton‐Valentine leukocidin (PVL) production is clinically associated with skin abscesses, soft tissues infections, bacteraemia and sepsis.… Click to show full abstract

Staphylococcus aureus is one of the most common pathogens in hospital environment and community. Panton‐Valentine leukocidin (PVL) production is clinically associated with skin abscesses, soft tissues infections, bacteraemia and sepsis. This study aimed to investigate the effects of the presence of genes lukF/S‐PV coding for PVL, in histological and haematological features during systemic infection, using a Swiss mice experimental model.

Keywords: staphylococcus aureus; panton valentine; valentine leukocidin

Journal Title: Journal of Applied Microbiology
Year Published: 2020

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