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Suilysin is a critical pore‐forming virulence factor of Streptococcus suis that has been demonstrated to substantially contribute to its pathogenicity. We have demonstrated that formononetin alleviates S. suis infection both… Click to show full abstract
Suilysin is a critical pore‐forming virulence factor of Streptococcus suis that has been demonstrated to substantially contribute to its pathogenicity. We have demonstrated that formononetin alleviates S. suis infection both in vivo and in vitro by targeting suilysin. However, the molecular mechanism of the effect is unclear. Our aim was to determine the molecular mechanism of the effect of formononetin on suilysin.
Keywords:
action structural;
structural modelling;
suilysin;
formononetin suilysin;
mode action;
modelling interaction
Journal Title: Journal of Applied Microbiology
Year Published: 2021
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Journal Title: Journal of Applied Microbiology
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!