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A commercial SnF2 toothpaste formulation reduces simulated human plaque biofilm in a dynamic typodont model

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We present a dynamic typodont biofilm model (DTBM) incorporating (1) human dentition anatomy, (2) fluid flow over intermittently fluid bathed tooth surfaces and (3) an oxic headspace to allow aerobic… Click to show full abstract

We present a dynamic typodont biofilm model (DTBM) incorporating (1) human dentition anatomy, (2) fluid flow over intermittently fluid bathed tooth surfaces and (3) an oxic headspace to allow aerobic and anaerobic niches to develop naturally, as a screening tool to assess the effect of stannous fluoride (SnF2) toothpaste against a simulated human plaque biofilm (SPB).

Keywords: plaque biofilm; snf2 toothpaste; biofilm; human plaque; dynamic typodont; simulated human

Journal Title: Journal of Applied Microbiology
Year Published: 2022

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