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K2p3.1, also known as TASK‐1, is a twin‐pore acid‐sensitive repolarizing K+ channel, responsible for a background potassium current that significantly contributes to setting the resting membrane potential of cardiac myocytes.… Click to show full abstract
K2p3.1, also known as TASK‐1, is a twin‐pore acid‐sensitive repolarizing K+ channel, responsible for a background potassium current that significantly contributes to setting the resting membrane potential of cardiac myocytes. Inhibition of IK2p3.1 alters cardiac repolarization and is proarrhythmogenic. In this study, we have examined the expression of K2p3.1 and function of this channel in tissue and myocytes from across the left ventricular free wall.
Keywords:
free wall;
k2p3 protein;
left ventricular;
ventricular free
Journal Title: Journal of Cardiovascular Electrophysiology
Year Published: 2019
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Journal Title: Journal of Cardiovascular Electrophysiology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!