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Multicenter experience with andexanet alfa for refractory pericardial bleeding during catheter ablation of atrial fibrillation

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Pericardial bleeding is a rare but life‐threatening complication of atrial fibrillation (AF) ablation. Patients taking uninterrupted oral anticoagulation (AC) may be at increased risk for refractory bleeding despite pericardiocentesis and… Click to show full abstract

Pericardial bleeding is a rare but life‐threatening complication of atrial fibrillation (AF) ablation. Patients taking uninterrupted oral anticoagulation (AC) may be at increased risk for refractory bleeding despite pericardiocentesis and administration of protamine. In such cases, andexanet alfa can be given to reverse rivaroxaban or apixaban. In this study, we aim to describe the rate of acute hemostasis and thromboembolic complications with andexanet for refractory pericardial bleeding during AF ablation.

Keywords: refractory pericardial; ablation; pericardial bleeding; atrial fibrillation; andexanet alfa

Journal Title: Journal of Cardiovascular Electrophysiology
Year Published: 2023

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