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BDA‐410 inhibits SARS‐CoV‐2 main protease activity and viral replication in mammalian cells

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neutralization assay. A viral neutralization assay determined the efficacy of BDA- 410 against SARS- CoV- 2 in the NR- 596 VeroE6 cell line. After staining with 0.2% crystal violet, the… Click to show full abstract

neutralization assay. A viral neutralization assay determined the efficacy of BDA- 410 against SARS- CoV- 2 in the NR- 596 VeroE6 cell line. After staining with 0.2% crystal violet, the plaques were counted and recorded, and the neutralization potency of BDA- 410 was quantified. All viral infection quantification assays were performed under BSL- 4 at the National Emerging Infectious Diseases Laboratories (NEIDL)

Keywords: inhibits sars; bda 410; cov main; main protease; sars cov; 410 inhibits

Journal Title: Journal of Cellular and Molecular Medicine
Year Published: 2022

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