Chronic pain presents a difficult clinical challenge because of the limited efficacy, the limiting adverse‐effect profile or the abuse potential of current analgesic options. Cebranopadol is a novel new agent… Click to show full abstract
Chronic pain presents a difficult clinical challenge because of the limited efficacy, the limiting adverse‐effect profile or the abuse potential of current analgesic options. Cebranopadol is a novel new agent in clinical trials that combines dual agonist action at opioid and nociceptin/orphanin FQ peptide (NOP) receptors. It is the first truly unique, centrally acting analgesic in several years. We here review the basic and clinical pharmacology of cebranopadol.
               
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