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Intentional use of carbapenem antibiotics for valproic acid toxicity: A case report

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The interaction between valproic acid (VPA) and carbapenem antibiotics is well described with previous reports suggesting a reduction in VPA half‐life between 47% and 90%. As described in this case,… Click to show full abstract

The interaction between valproic acid (VPA) and carbapenem antibiotics is well described with previous reports suggesting a reduction in VPA half‐life between 47% and 90%. As described in this case, this interaction might be beneficial in the setting of toxic VPA ingestion.

Keywords: intentional use; carbapenem antibiotics; case; valproic acid; use carbapenem

Journal Title: Journal of Clinical Pharmacy and Therapeutics
Year Published: 2018

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