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Nebivolol, a selective β1 adrenoreceptor antagonist, is predominantly metabolized by cytochrome P450 (CYP)2D6 and shows a wide interindividual variability in pharmacokinetics. The present study was conducted to evaluate the effects… Click to show full abstract
Nebivolol, a selective β1 adrenoreceptor antagonist, is predominantly metabolized by cytochrome P450 (CYP)2D6 and shows a wide interindividual variability in pharmacokinetics. The present study was conducted to evaluate the effects of the major CYP2D6 polymorphisms on nebivolol disposition in healthy Chinese volunteers.
Keywords:
healthy chinese;
cyp2d6 polymorphism;
pharmacokinetics nebivolol;
polymorphism pharmacokinetics;
cyp2d6;
influence cyp2d6
Journal Title: Journal of Clinical Pharmacy and Therapeutics
Year Published: 2020
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Journal Title: Journal of Clinical Pharmacy and Therapeutics
Year Published: 2020
Link to full text (if available)
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recommendations!