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Pharmacokinetics, safety and tolerability of long‐acting parenteral intramuscular injection formulations of doravirine

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Doravirine is a non‐nucleoside reverse transcriptase inhibitor indicated for the treatment of human immunodeficiency virus (HIV)‐1 infection. This phase 1 study in healthy adults investigated the pharmacokinetics, safety and tolerability… Click to show full abstract

Doravirine is a non‐nucleoside reverse transcriptase inhibitor indicated for the treatment of human immunodeficiency virus (HIV)‐1 infection. This phase 1 study in healthy adults investigated the pharmacokinetics, safety and tolerability of long‐acting parenteral (LAP) microsuspension formulations of doravirine administered as an intramuscular (IM) injection.

Keywords: long acting; safety tolerability; acting parenteral; pharmacokinetics safety; tolerability long; formulations doravirine

Journal Title: Journal of Clinical Pharmacy and Therapeutics
Year Published: 2020

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