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mTOR inhibitors possess narrow therapeutic range and substantial pharmacokinetic variability and the consequences from suboptimal dosing are serious. The aim of this review is to summarize the current knowledge about… Click to show full abstract
mTOR inhibitors possess narrow therapeutic range and substantial pharmacokinetic variability and the consequences from suboptimal dosing are serious. The aim of this review is to summarize the current knowledge about the factors influencing mTOR inhibitors pharmacokinetics and the possibility of using these relationships in order to improve its therapy individualization in solid organ transplanted patients.
Keywords:
pharmacokinetic principles;
mtor inhibitors;
mtor;
transplanted patients;
organ transplanted;
solid organ
Journal Title: Journal of Clinical Pharmacy and Therapeutics
Year Published: 2022
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Journal Title: Journal of Clinical Pharmacy and Therapeutics
Year Published: 2022
Link to full text (if available)
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recommendations!