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VANCOmycin dose adjustments comparing trough levels to the ratio of the area under de curve to the minimum inhibitory concentration method using a BAYESian approach: A feasibility study

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The latest published guidelines advocate for the area under the concentration‐time curve to minimal inhibitory concentration (AUC0‐24h/MIC) estimated with bayesian calculations. This recommended pharmacokinetic monitoring transition is not based on… Click to show full abstract

The latest published guidelines advocate for the area under the concentration‐time curve to minimal inhibitory concentration (AUC0‐24h/MIC) estimated with bayesian calculations. This recommended pharmacokinetic monitoring transition is not based on randomized controlled prospective data.

Keywords: inhibitory concentration; curve; area; vancomycin dose; concentration; dose adjustments

Journal Title: Journal of Clinical Pharmacy and Therapeutics
Year Published: 2022

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