A patient with mitochondrial diabetes mellitus developed diabetic ketoacidosis. During insulin treatment, although diabetic ketoacidosis improved, lactic acidosis unexpectedly worsened. This clinical course, named “switched metabolic acidosis,” could reflect the… Click to show full abstract
A patient with mitochondrial diabetes mellitus developed diabetic ketoacidosis. During insulin treatment, although diabetic ketoacidosis improved, lactic acidosis unexpectedly worsened. This clinical course, named “switched metabolic acidosis,” could reflect the unique pathophysiology of the mitochondrial disorder.
               
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