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Peroxisome proliferator‐activated receptor (PPAR)‐γ2 is a transcription factor crucial for regulating adipogenesis and glucose/lipid metabolism, and synthetic PPARγ ligands, such as thiazolidinediones, are effective oral medication for type 2 diabetes.… Click to show full abstract
Peroxisome proliferator‐activated receptor (PPAR)‐γ2 is a transcription factor crucial for regulating adipogenesis and glucose/lipid metabolism, and synthetic PPARγ ligands, such as thiazolidinediones, are effective oral medication for type 2 diabetes. Sirtuin 7 (SIRT7), a nicotinamide adenine dinucleotide‐dependent deacetylase, also controls metabolism. However, it is not known whether SIRT7 regulates the function of PPARγ2 by its deacetylation.
Keywords:
sirt7 regulates;
lipogenesis adipocytes;
deacetylation ppar;
sirt7;
regulates lipogenesis;
adipocytes deacetylation
Journal Title: Journal of Diabetes Investigation
Year Published: 2021
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Journal Title: Journal of Diabetes Investigation
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!