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Efficacy of ustekinumab after failure of infliximab CT‐P13 in a HLA‐Cw6‐positive patient affected by pityriasis rubra pilaris: monitoring with reflectance confocal microscopy (RCM) and optical coherence tomography (OCT)

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Pityriasis rubra pilaris (PRP) is a rare, chronic inflammatory skin disorder characterized by the presence of small follicular hyperkeratotic papules that coalesce into yellow-pink (salmon-colored) patches, usually beginning at the… Click to show full abstract

Pityriasis rubra pilaris (PRP) is a rare, chronic inflammatory skin disorder characterized by the presence of small follicular hyperkeratotic papules that coalesce into yellow-pink (salmon-colored) patches, usually beginning at the head and neck and often resulting in generalized erythroderma1. Other main clinical features are “islands” of sparing within the affected skin, palmoplantar keratoderma, nail dystrophy, oral involvement and eventually ectropion. The age of onset has a peak between 50 and 70 years but a juvenile presentation is not uncommon. This article is protected by copyright. All rights reserved.

Keywords: pityriasis rubra; rubra pilaris; microscopy

Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2017

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