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Fatal infection of Pneumocystis jiroveci pneumonia in a pemphigus patient treated with rituximab

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Rituximab is an effective treatment for pemphigus and can be considered as a first-line treatment for severe cases.1-4 Rituximab increases the risk of infection with Pneumocystis jiroveci pneumonia (PJP), an… Click to show full abstract

Rituximab is an effective treatment for pemphigus and can be considered as a first-line treatment for severe cases.1-4 Rituximab increases the risk of infection with Pneumocystis jiroveci pneumonia (PJP), an opportunistic pathogen, especially in hematopoietic stem cell transplant and Wegener's granulomatosis, with a high associated mortality rate up to 30%.5 The risk of PJP infection in pemphigus patients treated with rituximab has been underreported to date. This article is protected by copyright. All rights reserved.

Keywords: infection; jiroveci pneumonia; infection pneumocystis; treated rituximab; pemphigus; pneumocystis jiroveci

Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2017

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