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Expression of monoacylglycerol lipase as a marker of tumour invasion and progression in malignant melanoma

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Accumulating evidence suggests that the lipid lytic enzyme monoacylglycerol lipase (MAGL) promotes tumour invasion and metastasis through up‐regulation of pro‐tumorigenic signalling lipids in several tumour cell lines. However, the expression… Click to show full abstract

Accumulating evidence suggests that the lipid lytic enzyme monoacylglycerol lipase (MAGL) promotes tumour invasion and metastasis through up‐regulation of pro‐tumorigenic signalling lipids in several tumour cell lines. However, the expression status of MAGL in clinical melanoma tissues and its clinicopathological significance remain unclear.

Keywords: melanoma; monoacylglycerol lipase; tumour invasion

Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2017

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