Peripheral T-cell lymphomas not otherwise specified (PTCLs-NOS) have been defined as a kind of "Pandora's box", because of the broad morphologic spectrum, which features a prevalent nodal involvement and an… Click to show full abstract
Peripheral T-cell lymphomas not otherwise specified (PTCLs-NOS) have been defined as a kind of "Pandora's box", because of the broad morphologic spectrum, which features a prevalent nodal involvement and an aggressive, yet non-specific clinical course1,2 . PTCLs-NOS usually have a nodal presentation, while a skin spread occurs in approximately 20% of cases3 being regarded as a worse prognostic factor4,5,6 . PTCLs-NOS featuring skin lesions present at least six months before a hypothetical systemic involvement are regarded as a separate entity, named primary cutaneous PTCLs-NOS (PC-PTCLs-NOS)3,4,7 . This article is protected by copyright. All rights reserved.
               
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