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The therapeutic potential of TNF‐α antagonists in toxic epidermal necrosis: insights from two cases and adverse event reports

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Treatment of toxic epidermal necrolysis (TEN) represents a significant challenge for the clinicians. Several recent reports proposed that inhibition of tumour necrosis factor alfa (TNF-α) may improve the prognosis of… Click to show full abstract

Treatment of toxic epidermal necrolysis (TEN) represents a significant challenge for the clinicians. Several recent reports proposed that inhibition of tumour necrosis factor alfa (TNF-α) may improve the prognosis of TEN1-5 . A recent study now provided additional data and concluded that TNF-α blockade may indeed be beneficial for TEN outcome1 . This article is protected by copyright. All rights reserved.

Keywords: necrosis; potential tnf; tnf; tnf antagonists; therapeutic potential; toxic epidermal

Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2018

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