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Probiotics for recurrent idiopathic aphthous stomatitis in adults: a placebo‐controlled randomized trial

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Sir, recurrent idiopathic aphtosous stomatitis (RIAS) is a frequent disorder that induces a marked alteration of the quality of life of affected individuals. Thalidomide is the only treatment that demonstrated… Click to show full abstract

Sir, recurrent idiopathic aphtosous stomatitis (RIAS) is a frequent disorder that induces a marked alteration of the quality of life of affected individuals. Thalidomide is the only treatment that demonstrated its efficacy in a multicenter placebo controlled trial. However, the use of thalidomide is limited by its side-effects and it is usually reserved for the most severe cases.

Keywords: probiotics recurrent; trial; placebo controlled; recurrent idiopathic; idiopathic aphthous; stomatitis

Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2020

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