Biologics are a fundamental therapeutic resource for patients with moderate to severe chronic plaque psoriasis because they well conjugate effectiveness and safety. Several classes of biologics are available, including TNF-α… Click to show full abstract
Biologics are a fundamental therapeutic resource for patients with moderate to severe chronic plaque psoriasis because they well conjugate effectiveness and safety. Several classes of biologics are available, including TNF-α inhibitors (infliximab, etanercept, adalimumab and certolizumab pegol), IL-12/23 inhibitor (ustekinumab), IL-17 inhibitors (secukinumab, ixekizumab and brodalumab) and IL-23 inhibitors (guselkumab, risankizumab and tildrakizumab). Each class of biologics has distinct characteristics.
               
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