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Frequency and characteristics of pruritus in patients with monoclonal gammopathy: a case–control study

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Chronic pruritus (CP) is a frequent symptom in many skin and systemic diseases(1), including haematological malignancies. It is described in 30% of Hodgkin lymphoma patients and in patients with myeloproliferative… Click to show full abstract

Chronic pruritus (CP) is a frequent symptom in many skin and systemic diseases(1), including haematological malignancies. It is described in 30% of Hodgkin lymphoma patients and in patients with myeloproliferative disorders, particularly in polycythaemia vera(2,3). Serum protein electrophoresis (SPEP) is recommended in laboratory screening for CP(4). However, the literature about pruritus in monoclonal gammapathies (MGs) is scarce(5-7). The aim of this study was to determine the frequency and clinical characteristics of pruritus in patients with MGs in comparison to controls with normal SPEP results.

Keywords: characteristics pruritus; frequency characteristics; pruritus patients; study; patients monoclonal

Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2020

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