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Minoxidil is an antihypertensive agent and hair growth promoter. Minoxidil is a pro-drug that requires conversion to minoxidil sulfate by the sulfotransferase enzymes to be biologically active. Previously, we identified… Click to show full abstract
Minoxidil is an antihypertensive agent and hair growth promoter. Minoxidil is a pro-drug that requires conversion to minoxidil sulfate by the sulfotransferase enzymes to be biologically active. Previously, we identified the sulfotransferases isoenzyme SULT1A1 as the predominant sulfotransferase responsible for minoxidil sulfonation in the outer root sheet (ORS) of hair follicles.
Keywords:
minoxidil;
hair;
sulfotransferase enzyme;
enzyme sult1a1;
minoxidil sulfotransferase;
sulfotransferase
Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2020
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Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!