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Talimogene laherparepvec can initiate plasma cell invasion into infiltrated melanoma lesions – a case series

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Talimogene laherparepvec (T-VEC) is a genetically engineered herpes simplex virus type 1 (HSV-1) and used in locally advanced melanoma patients. Its mode of action is not fully understood. We present… Click to show full abstract

Talimogene laherparepvec (T-VEC) is a genetically engineered herpes simplex virus type 1 (HSV-1) and used in locally advanced melanoma patients. Its mode of action is not fully understood. We present three cases where T-VEC caused monoclonal as well as polyclonal B-cell infiltration.

Keywords: laherparepvec initiate; talimogene laherparepvec; plasma cell; initiate plasma; talimogene

Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2020

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