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Distinctive clinical and histological characteristics of atrophic and hypertrophic facial photoageing

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Photoageing describes complex cutaneous changes which occur following chronic exposure to solar ultraviolet radiation (UVR). Amongst White Northern Europeans, facial photoageing appears as distinct clinical phenotypes: ‘hypertrophic’ photoageing (HP) and… Click to show full abstract

Photoageing describes complex cutaneous changes which occur following chronic exposure to solar ultraviolet radiation (UVR). Amongst White Northern Europeans, facial photoageing appears as distinct clinical phenotypes: ‘hypertrophic’ photoageing (HP) and ‘atrophic’ photoageing (AP). Deep, coarse wrinkles predominate in individuals with HP, whereas those with AP have relatively smooth, unwrinkled skin with pronounced telangiectasia. AP individuals have an increased propensity for developing keratinocyte cancers.

Keywords: facial photoageing; histological characteristics; clinical histological; atrophic hypertrophic; distinctive clinical; characteristics atrophic

Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2020

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