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SARS‐CoV‐2 mRNA vaccine‐associated fixed drug eruption

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A 26-year-old, healthy, female nurse on no regular medication, developed a mildly pruritic, erythematous, annular patch with faint, central clearing on her left shoulder (Figure 1a). The patient had received… Click to show full abstract

A 26-year-old, healthy, female nurse on no regular medication, developed a mildly pruritic, erythematous, annular patch with faint, central clearing on her left shoulder (Figure 1a). The patient had received the first dose of the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine in the same arm 15 days prior to the development of the lesion. The injection site was 7cm distal to the evolving patch. Over the span of 2 days, the patch developed a shallow, central erosion surrounded by a halo of erythema (Figure 1b) and subsequently started to resolve spontaneously. The patient had also experienced facial flushing 15 minutes after the vaccine was administered.

Keywords: mrna vaccine; cov mrna; associated fixed; sars cov; vaccine associated

Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2021

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