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Microbial dysbiosis in a mouse model of atopic dermatitis mimics shifts in human microbiome and correlates with the key pro‐inflammatory cytokines IL‐4, IL‐33 and TSLP

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Cutaneous bacterial dysbiosis is a characteristic hallmark of atopic dermatitis (AD), and it decisively influences the severity of the disease. Despite this, frequently used murine models of AD have not… Click to show full abstract

Cutaneous bacterial dysbiosis is a characteristic hallmark of atopic dermatitis (AD), and it decisively influences the severity of the disease. Despite this, frequently used murine models of AD have not been characterized regarding the changes in skin microbiome communities.

Keywords: atopic dermatitis; dysbiosis; microbial dysbiosis; dysbiosis mouse

Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2022

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