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Non‐AIDS‐associated chronic diseases in HIV+ patients have been on the rise since the advent of antiretroviral therapy. Especially cardiovascular diseases and disruption in the gastrointestinal tract have limited health‐related quality… Click to show full abstract
Non‐AIDS‐associated chronic diseases in HIV+ patients have been on the rise since the advent of antiretroviral therapy. Especially cardiovascular diseases and disruption in the gastrointestinal tract have limited health‐related quality of life (QoL). Several of those complications have been associated with chronic systemic inflammation. Short‐chain fatty acids (SCFA), with propionate as one of the major compounds, have been described as an important link between gut microbiota and the immune system, defining the pro‐ and the anti‐inflammatory milieu through direct and indirect regulation of T‐cell homeostasis. The effects of dietary supplementation of sodium propionate (SP) in people living with HIV (PLHIV) have not yet been investigated prior to this study.
Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2022
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