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Myrtus communis and Celastrol enriched plant cell culture extracts control together the pivotal role of Cutibacterium acnes and inflammatory pathways in acne

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Acne is a multifactorial inflammatory disease of the pilosebaceous unit in which Cutibacterium acnes is one of the main triggers. A strong predominance of C. acnes phylotype IA1 is present… Click to show full abstract

Acne is a multifactorial inflammatory disease of the pilosebaceous unit in which Cutibacterium acnes is one of the main triggers. A strong predominance of C. acnes phylotype IA1 is present in acne skin with higher biofilm organization and virulence, promoting local immuno‐inflammation, especially the Th17 pathway.

Keywords: celastrol enriched; myrtus communis; cutibacterium acnes; cutibacterium; communis celastrol; enriched plant

Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2023

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