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Multispectral optoacoustic tomography to differentiate between lymph node metastases and coronavirus‐19 vaccine‐associated lymphadenopathy

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Worldwide mass vaccination for COVID‐19 started in late 2020. COVID‐19 vaccines cause benign hypermetabolic lymphadenopathies. Clinical stratification between vaccine‐associated benign lymphadenopathies and malignant lymphadenopathies through ultrasound, MRI or FDG PET‐CT… Click to show full abstract

Worldwide mass vaccination for COVID‐19 started in late 2020. COVID‐19 vaccines cause benign hypermetabolic lymphadenopathies. Clinical stratification between vaccine‐associated benign lymphadenopathies and malignant lymphadenopathies through ultrasound, MRI or FDG PET‐CT is not feasible. This leads to unnecessary lymph node biopsies, excisions and even radical lymph node dissections. Therefore, to avoid unnecessary surgeries, we assessed whether noninvasive multispectral optoacoustic tomography (MSOT) enables a better differentiation between benign and malignant lymphadenopathies.

Keywords: lymph node; vaccine associated; optoacoustic tomography; multispectral optoacoustic; lymph

Journal Title: Journal of the European Academy of Dermatology and Venereology
Year Published: 2023

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