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BACKGROUND The most important advance of precision medicine (PM) has been a specific way to define and understand disease. However, PM may fail to be therapeutically effective if diseases are… Click to show full abstract
BACKGROUND The most important advance of precision medicine (PM) has been a specific way to define and understand disease. However, PM may fail to be therapeutically effective if diseases are natural kinds. OBJECTIVE To attest adverse consequences of treatments suggested by PM that do not generalize well. METHODS Conceptual analysis of PM; Epistemology of clinical reasoning; Cases that show diseases as natural kinds to clash with epistemology of PM. RESULTS Contemplation of future research options that could clarify the position of PM under the conception of diseases as natural kinds. CONCLUSION Need for improved design of future interventions that better acknowledge problematic epistemology of PM.
Journal Title: Journal of evaluation in clinical practice
Year Published: 2022
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