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Prediction of carotid intima–media thickness in obese patients with low prevalence of comorbidities by serum copper bioavailability

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Western societies, with growing prevalence, suffer from various metabolic diseases like obesity and hepatic steatosis, better defined as non‐alcoholic fatty liver disease, or cardiovascular (CV) diseases that are strictly linked… Click to show full abstract

Western societies, with growing prevalence, suffer from various metabolic diseases like obesity and hepatic steatosis, better defined as non‐alcoholic fatty liver disease, or cardiovascular (CV) diseases that are strictly linked to each other. The association of their occurrence with the altered homeostasis of metals is an intriguing issue. Copper in particular was identified as key player in various metabolic derangements. On these bases, we aimed at investigating the possible association of serum copper levels with an indicator of early CV risk as the intima–media thickness (IMT) of carotid artery and its predictive value in a selected population of obese patients.

Keywords: serum copper; copper; prevalence; obese patients; intima media; media thickness

Journal Title: Journal of Gastroenterology and Hepatology
Year Published: 2018

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