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Compound polysaccharides ameliorate experimental colitis by modulating gut microbiota composition and function

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Inflammatory bowel disease results from a dysregulated immune response to intestinal microbial flora in individuals with genetic predisposition(s). This study aimed to determine the effects of compound polysaccharides (CP) containing… Click to show full abstract

Inflammatory bowel disease results from a dysregulated immune response to intestinal microbial flora in individuals with genetic predisposition(s). This study aimed to determine the effects of compound polysaccharides (CP) containing yam polysaccharide and inulin on the rat model of colitis induced by 2,4,6‐trinitrobenzenesulfonic acid (TNBS) and to explain the mechanism in terms of gut microbiota composition and function.

Keywords: compound polysaccharides; colitis; gut microbiota; composition function; microbiota composition

Journal Title: Journal of Gastroenterology and Hepatology
Year Published: 2018

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