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Association of TRAP1 with infliximab‐induced mucosal healing in Crohn's disease

Anti‐tumor necrosis factor (TNF) agents, such as infliximab (IFX), have been increasingly used to induce and maintain disease remission in patients with Crohn's disease (CD). Despite a considerable non‐response rate,… Click to show full abstract

Anti‐tumor necrosis factor (TNF) agents, such as infliximab (IFX), have been increasingly used to induce and maintain disease remission in patients with Crohn's disease (CD). Despite a considerable non‐response rate, little is known about the genetic predictors of response to anti‐TNF therapy in CD. Our aim in this study was to investigate the genetic factors associated with response to anti‐TNF therapy in patients with CD.

Keywords: association trap1; trap1 infliximab; disease; induced mucosal; infliximab induced; crohn disease

Journal Title: Journal of Gastroenterology and Hepatology
Year Published: 2019

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