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Prevention of post‐endoscopic retrograde cholangiopancreatography pancreatitis with a combination of pharmacological agents based on rectal non‐steroidal anti‐inflammatory drugs: A systematic review and network meta‐analysis

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Rectally administered non‐steroidal anti‐inflammatory drugs (NSAIDs) are effective but suboptimal in the prevention of post‐endoscopic retrograde cholangiopancreatography pancreatitis or PEP. New trials with the combination of rectal NSAIDs and other… Click to show full abstract

Rectally administered non‐steroidal anti‐inflammatory drugs (NSAIDs) are effective but suboptimal in the prevention of post‐endoscopic retrograde cholangiopancreatography pancreatitis or PEP. New trials with the combination of rectal NSAIDs and other pharmacological agents have been conducted. This network meta‐analysis (NMA) aimed to determine the relative efficacy of combination regimens and identify an optimal regimen for preventing PEP.

Keywords: anti inflammatory; combination; prevention post; steroidal anti; non steroidal; inflammatory drugs

Journal Title: Journal of Gastroenterology and Hepatology
Year Published: 2020

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