Of the three patients who progressed to esophageal adenocarcinoma during their surveillance period, two had early stage cancer (IA), which was suitable for curative treatment;the third patient had metastatic disease… Click to show full abstract
Of the three patients who progressed to esophageal adenocarcinoma during their surveillance period, two had early stage cancer (IA), which was suitable for curative treatment;the third patient had metastatic disease at time of diagnosis. Twenty-one patients had endoscopy performed, with histological examination showing that eight had mild active colitis ± crypt architecture distortion, four had a lymphocytic colitis-like pattern, one had microscopic colitis, and eight had normal histology (Table 1). SP 3 sp Of the 55 patients with colitis who received medical therapy, 29 received only loperamide, 17 required oral corticosteroids (CS), six required intravenous CS, and three required infliximab. Fifty-three patients responded after 1 month (range, 1-10 months), and seven patients had recurrent episodes of diarrhea, requiring courses of oral CS (five patients), intravenous CS (four patients), or infliximab (two patients). Hematological malignancies and end-stage renal disease are recognized among the main underlying causes. SP 1 sp In a retrospective cohort study of 2334 patients with systemic amyloidosis, only 3.2% of patients were found to have biopsy-proven gastrointestinal amyloidosis. SP 2 sp Bleeding, malabsorption, protein-losing gastroenteropathy, and chronic gastrointestinal dysmotility are recognized clinical consequences. [Extracted from the article] Copyright of Journal of Gastroenterology & Hepatology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
               
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