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Diagnosis of abdominal tuberculosis by multi‐targeted (mpt64 and IS6110) loop‐mediated isothermal amplification assay

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Diagnosis of abdominal TB is an exigent task due to variable anatomical sites and non‐specific clinical manifestations that closely resemble other diseases. Most of the available diagnostic modalities yield low… Click to show full abstract

Diagnosis of abdominal TB is an exigent task due to variable anatomical sites and non‐specific clinical manifestations that closely resemble other diseases. Most of the available diagnostic modalities yield low sensitivities and need expertise to handle the specialized equipment. Hence, there is an urgent need to develop a rapid and reliable diagnostic test, so as to reduce the unnecessary morbidity. Therefore, we designed a multi‐targeted loop‐mediated isothermal amplification (MT‐LAMP) for diagnosing abdominal TB.

Keywords: diagnosis abdominal; isothermal amplification; mediated isothermal; multi targeted; loop mediated

Journal Title: Journal of Gastroenterology and Hepatology
Year Published: 2022

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