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Analysis of Immunometabolic Profiles in Patients With Chronic Drug‐Induced Liver Injury and Validation in Mice to Reveal Potential Mechanisms

The mechanism underlying chronic drug‐induced liver injury (DILI) remains unclear. Immune activation is a common feature of DILI progression and is closely associated with metabolism. We explored the immunometabolic profile… Click to show full abstract

The mechanism underlying chronic drug‐induced liver injury (DILI) remains unclear. Immune activation is a common feature of DILI progression and is closely associated with metabolism. We explored the immunometabolic profile of chronic DILI and the potential mechanism of chronic DILI progression.

Keywords: liver injury; induced liver; chronic drug; drug induced

Journal Title: Journal of Gastroenterology and Hepatology
Year Published: 2025

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